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Common Cattle Diseases and How to Treat Them

Common Cattle Diseases and How to Treat Them

Writer: Courtney J Garrett
Courtney J Garrett
Aug 26
10 min read

Updated: Sep 19

(Posted March 2023, Updated August 2026)


Summary:

This guide covers the most common cattle diseases, their symptoms, and effective treatment options. By understanding the early signs of illness and maintaining proper herd health management, cattle producers can quickly identify issues, prevent the spread of disease, and work with veterinarians to ensure a healthy, thriving herd.


Key Takeaways

  • Monitor Behavior: Early detection of physical and behavioral changes, like loss of appetite, is critical for treating sick cattle.

  • Treat Promptly: Common ailments like Bovine Respiratory Disease (BRDC), Pinkeye, and Foot Rot require specific veterinary or antibiotic treatments.

  • Maintain Hygiene: Clean pens, dry feeders, and fresh water sources help prevent the spread of infectious bacterial diseases.

  • Track Health Data: Using cattle management software helps track cattle herd health and catch illnesses before they spread.

  • Consult a Vet: Always consult your local livestock veterinarian for an accurate diagnosis and appropriate prescription medications.


Common Cattle Diseases and How to Treat Them

Recognizing Sick Cattle

It goes without saying that it is important to know the signs of cattle diseases so that you can keep your cattle herd healthy and thriving. Some diseases are easy to identify, but other signs are more subtle. The symptoms of a disease can be physical or behavioral, and some may be both.



So what are some common signs? Well, if your cow or bull has diarrhea or is coughing up mucus, that’s an obvious sign that something isn’t right with them. But there are some other things to look out for as well:


  • Behavioral changes: Some cows will become restless and irritable when they have a fever; others become lethargic and stop eating altogether when they get sick (or even go into shock). Be especially aware if your cow starts acting out of character—this could mean she needs treatment immediately.

  • Loss of appetite: This usually happens before any other type of symptom shows up because bovines tend not to eat when feeling under the weather.


Keeping track of these early indicators is vital for a rapid response, and utilizing tools like the best software for cattle management can easily streamline your farm's health records.

Common Cattle Diseases & Treatments

Bovine Respiratory Disease Complex (BRDC)

Bovine Respiratory Disease Complex (BRDC) occurs mainly in young calves around weaning time. It is a respiratory tract infection that can have several causes, from bacterial to viral pathogens.


Symptoms of BRDC include:

• Depression and fatigue

• Lack of interest in feed

• Coughing

• Head extension

• Rapid, shallow breathing

• Isolation from the rest of the herd

• Fever


Early identification and treatment of this disease is essential for the best chance of recovery. It is recommended that affected animals be quarantined to prevent the spread of the disease among the herd.


Treatment of BRDC:

Treatment includes injectable prescription antibiotics and anti-inflammatories. There are quite a few antibiotics to choose from, many of which are specific to local resistance levels. Check with your veterinarian to decide on the most effective one for your cattle.


Pinkeye

Pinkeye (bovine keratoconjunctivitis) is a highly infectious disease that is formally known as bovine keratoconjunctivitis. It is a bacterial infection that affects the eyes and causes irritation. It is a common disease in cattle of all ages.


The bacteria that cause pinkeye enter through an animal's tear ducts or nares (nostrils) and multiply rapidly on the surface of the eye.


Affected animals may have watery eyes or discharge from their nostrils, along with crusting around their eyes and eyelids. This crusting is caused by heavy mucous production to keep out invading germs; however, it can lead to secondary infections if left untreated.


  • Symptoms: Eyelid squinting, excessive tearing, and cloudiness over parts or all of the eye.

  • Treatment: Over-the-counter medications, injectable oxytetracycline, topical sprays, and eye patches are effective treatments.


Foot Rot in Cattle

Foot rot is a bacterial infection that causes lameness in cattle. It's caused by a type of bacteria called Fusobacterium necrophorum, which can enter your cow's body through cuts or puncture wounds on her hooves.


It's most common in the summer months, though it can occur at any time of year depending on conditions and the type of bacteria involved.


Good hygiene practices are important for preventing foot rot and other diseases that affect your herd.


Good hygiene for your livestock includes:

• Keeping pens clean

• Keeping feeders clean and dry

• Not overcrowding animals into pens or feeding areas

• Avoiding dirty water sources like creeks or ponds (provide plenty of fresh water)


Foot rot can spread quickly through your herd if left untreated—it’s important to know how to spot symptoms so you can take action before the situation gets out of control!


  • Symptoms: Lameness, swelling of the foot, and reduced grazing.

  • Treatment & Prevention: Treat with veterinary-prescribed antibiotics and check hooves for foreign objects. Prevent outbreaks by keeping pens clean, ensuring dry feeders, avoiding overcrowding, and providing fresh water instead of dirty ponds.


Infectious Bovine Rhinotracheitis (IBR)

IBR is a contagious viral disease that affects cattle. It usually affects the respiratory tract and reproductive system of cattle. It is caused by a virus called bovine herpesvirus type 1 (BHV-1).

This disease is highly infectious and can be prevalent in areas where cattle are in close contact with each other, such as feedlots and during transportation.


  • Symptoms: Fever, sudden coughing, nasal/eye discharge, ulcers on the nose or mouth, swollen lymph nodes, and lethargy.


  • Treatment: While no direct antiviral treatment exists, antibiotics are used to fight secondary bacterial infections. Reduce stress, quarantine sick animals, and ensure access to clean feed and water.

Bovine Viral Diarrhea (BVD)

BVD is a contagious disease in cattle that is caused by a virus. It is an economically important disease in cattle because it causes reduced milk production and weight gain in dairy cattle.

BVD typically affects young calves between 3 weeks and three months old but can affect older animals as well.


  • Symptoms: Fever, depression, loss of appetite, diarrhea, and reduced milk production.

  • Treatment: Most cases resolve in 2-3 weeks. Antibiotics are given to prevent secondary infections, along with supportive care.



Blackleg

Blackleg is caused by Clostridium chauvoei, a bacterium that affects the muscles. The disease is not highly contagious, but it can be transmitted through contaminated feed or water.


  • Symptoms: Severe lameness due to muscle inflammation and rapid deterioration of muscle fibers.


  • Treatment: Treat promptly with antibiotics such as tiamulin or tylosin.



Coccidiosis:

Coccidiosis is a common disease in cattle that is caused by a protozoan parasite called Eimeria. The parasite infects the intestines of cattle and causes diarrhea, fever, listlessness, and dehydration. Cattle can get this infection through contaminated feed or water. Symptoms usually appear within 7-10 days after exposure.


  • Symptoms: Abdominal pain, diarrhea, loss of appetite, and high fever (103-105°F).


  • Treatment: Isolate affected cattle immediately. Administer fluids for dehydration and antibiotics for secondary infections.


Johne's Disease:

Johne’s Disease is a bacterial infection that causes diarrhea, weight loss, and chronic wasting in cattle. The spread of Johne's disease is thought to be due to the presence of Mycobacterium avium subsp. paratuberculosis (MAP) in livestock feces.


  • Symptoms: Chronic diarrhea and severe weight loss, leading to fatal dehydration in young calves.


  • Treatment: Unfortunately, there is no cure for Johne’s disease. Animals that test positive should be culled to protect the rest of the herd.


Once an animal has been exposed to MAP, it will remain infected for life—or as long as it produces milk. However, the bacteria do not always cause clinical signs of illness in affected animals. this is why Johne’s disease is sometimes called “fatal peritonitis.” Young animals that consume contaminated colostrum often die during their first few weeks after birth from dehydration caused by chronic diarrhea.


White Muscle Disease:

This disease is caused by a deficiency of the element selenium in the soil that cattle graze on. This results in cattle becoming deficient in this nutrient.


  • Symptoms: Muscle weakness, muscle damage, and stillborn or weak calves.


  • Treatment & Prevention: Administer sodium selenite and vitamin E emulsions to affected animals. Prevent the disease by providing selenium injections to newborns and mineral supplements to adults, but avoid over-supplementing to prevent toxicity.

Here are a few other vaccinations you should consider.

7-way or 8-way Clostridial, viral respiratory vaccines).


Mastitis: 

Mastitis is an inflammation of the mammary gland (udder) and is most commonly caused by a bacterial infection. While it is heavily monitored in dairy cattle, it is also a very common and costly disease in beef cow-calf operations. It can lead to reduced milk production and negatively impact calf weaning weights.


  • Symptoms: Swollen, hot, red, or painful udder, abnormal milk (clots, flakes, or watery consistency), fever, loss of appetite, and lethargy.

  • Treatment & Prevention: Treat promptly with veterinary-prescribed intramammary or systemic antibiotics and anti-inflammatories. Prevent outbreaks by maintaining clean, dry bedding, ensuring good milking hygiene, and keeping pastures and calving areas free of deep mud and standing water.


Bloat:

Bloat is a highly common and potentially fatal digestive disorder in which excess gas accumulates in the rumen and cannot be expelled. It generally presents in two forms: frothy bloat, typically caused by grazing lush, high-legume pastures, and free-gas bloat, which is more commonly seen in feedlots on high-grain diets.

  • Symptoms: Noticeable swelling on the left side of the abdomen, restlessness, signs of severe discomfort (such as kicking at the belly), rapid or labored breathing, and reluctance to move.

  • Treatment & Prevention: Severe cases require immediate veterinary intervention to relieve gas pressure via a stomach tube or trocar. Prevent bloat by introducing cattle to lush pastures gradually, feeding dry hay before turning them out to graze, and providing access to anti-bloat supplements like poloxalene blocks.


Grass Tetany:

Grass Tetany is a rapidly progressing and often fatal metabolic disease caused by a severe deficiency of magnesium in the blood. It most frequently occurs in the spring when cattle are turned out to graze on lush, rapidly growing, early-season pasture that is high in moisture and low in absorbable magnesium.

  • Symptoms: Muscle twitching, ear flicking, staggered or uncoordinated gait, uncharacteristically aggressive behavior, convulsions, and eventually coma or death.

  • Treatment & Prevention: Treat immediately with a slow intravenous injection of a calcium and magnesium solution administered by a veterinarian. Prevent the disease by providing high-magnesium mineral supplements (blocks or tubs) to the herd starting two to three weeks prior to spring turnout.


Biosecurity Best Practices: 

Protecting your cattle from the diseases listed above starts with a strong defense. Implementing strict biosecurity measures is the most effective way to prevent the introduction and spread of pathogens within your operation. Incorporate these actionable protocols into your management routine:

  • Quarantine New Arrivals: Always isolate new purchases or animals returning from shows in a separate pen for 14 to 30 days to monitor for illness before introducing them to the main herd.

  • Disinfect Equipment: Regularly clean and disinfect shared equipment, livestock trailers, halters, and veterinary tools (especially needles and taggers) to prevent cross-contamination.

  • Control Visitor Access: Limit unnecessary vehicular and foot traffic in animal areas. Require visitors, vets, and nutritionists to wear clean boots or use disinfecting footbaths upon entry.

  • Manage Pests: Actively control rodent, bird, and insect populations around feed storage and barns, as these pests are common vectors for spreading bacterial and viral diseases.


Nutrition and Immunity

A herd's ability to fend off infections and recover from illness is directly tied to its nutritional status. Providing a well-balanced diet ensures that cattle have the physical resources necessary to mount a strong, rapid immune response when exposed to pathogens, making it a cornerstone of disease prevention.

  • Protein and Energy: Maintaining an optimal Body Condition Score (BCS) through adequate energy and protein intake ensures the animal has the reserves needed to fight off infections rather than depleting its own body tissues during illness.

  • Vitamins: Vitamins A and E are crucial for maintaining the integrity of mucous membranes, which are the first line of defense against respiratory infections and Pinkeye and also support overall immune cell function.

  • Trace Minerals: Minerals like zinc, copper, and selenium are vital for vaccine efficacy, tissue repair, and hoof integrity (which helps prevent issues like Foot Rot). Proper selenium supplementation is also the direct preventative measure for White Muscle Disease.

  • Colostrum Quality: For newborn calves, initial immunity is completely dependent on receiving high-quality colostrum within the first few hours of life. Well-nourished cows produce superior colostrum, giving their calves a critical head start against early-life threats like BRDC and Coccidiosis.


Veterinary signs

Cattle Vital Sign Quick Reference:

Knowing a cow's normal vital signs establishes a baseline, making it much easier to detect when an animal is fighting off an infection or experiencing metabolic stress. Keep this quick reference handy when evaluating a potentially sick animal:

  • Rectal Temperature: 101.5°F to 102.8°F. A temperature consistently over 103°F generally indicates a fever and active infection.

  • Heart Rate (Pulse): 40 to 80 beats per minute. You can check the pulse by feeling the artery on the underside of the tail, close to the base.

  • Respiration Rate: 10 to 30 breaths per minute. Observe the rise and fall of the flank to count breaths. Rapid, shallow breathing is a key indicator of respiratory distress (like BRDC) or heat stress.

  • Rumen Contractions: 1 to 2 contractions per minute. Press your fist firmly into the left flank; a healthy, active rumen will push back against your hand. A quiet or still rumen is a strong early indicator of illness or digestive disorders like bloat.


Managing Overall Herd Health

Monitoring your cattle's Body Condition Score (BCS) and utilizing modern cattle management software helps you easily keep track of your cattle herd health. Catching these common diseases early makes a massive difference in recovery rates. If you spot any of the symptoms mentioned above, contact your local livestock veterinarian immediately for an accurate diagnosis and treatment plan.


Wrapping Up

Keeping your cattle herd healthy doesn't have to be overwhelming, but it does require a keen eye and a proactive approach. By familiarizing yourself with the signs of these common diseases, maintaining strong biosecurity and nutrition programs, and utilizing modern management software, you can catch illnesses early and minimize their impact. Remember, you don't have to navigate herd health alone. Establish a strong relationship with your local large-animal veterinarian can be a very valuable step you can take to ensure your operation remains productive and your cattle stay healthy for years to come.


Happy Farming!


Sources:


Frequently Asked Questions (FAQ)

What is the first sign that a cow might be sick?

Loss of appetite is usually the first indicator that a bovine is unwell. You should also closely watch for behavioral changes like lethargy, isolation, or restlessness.

Yes, foot rot can spread rapidly through a herd if animals share muddy, dirty, or overcrowded pens. Good hygiene and dry living conditions are essential for prevention.

No, there is currently no treatment or cure for Johne's disease. Infected animals remain contagious for life and are typically culled to prevent spreading the bacteria to the rest of the herd.

You should contact a veterinarian as soon as you notice severe behavioral changes, persistent coughing, high fever, or signs of contagious diseases like IBR or BRDC. Early intervention improves recovery chances and protects the broader herd.


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